Hydrobiome Serum

Epicutis

Hydrobiome Serum

4.9 · 170+ reviews
$275.00

A lightweight microbiome-balancing serum that calms, clears and strengthens the skin barrier, powered by the Signum actives TCP and TPNa.

  • Balances the skin microbiome
  • Targets breakouts & blemishes
  • Calms irritation
  • Strengthens the barrier
  • Antioxidant protection

What's inside

  • TCP (Disodium tetramethylhexadecenylcysteine formylprolinate)
  • TPNa (Sodium tocopheryl phosphate)
  • Sodium hyaluronate

Size50ml

Free clinic pickup, or flat-rate shipping Australia-wide.

Free clinic pickup Flat-rate AU shipping Afterpay at checkout Cruelty-free formulas Therapist-selected Ask us before you buy

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Overview

What is Hydrobiome Serum?

Hydrobiome Serum is a lightweight, fast-absorbing microbiome-balancing serum designed to improve overall skin health by balancing the skin's microbiome and strengthening the barrier. It brings together two clinically proven Signum Biosciences actives.

TCP, a patented TLR2 modulator, calms irritation and targets breakouts, clinically shown to improve the clarity and balance of acne-prone skin more effectively than conventional actives like benzoyl peroxide or salicylic acid, without the dryness or irritation, by selectively targeting C. acnes while preserving your skin's beneficial flora. TPNa, a next-generation water-soluble vitamin E, adds consistent antioxidant protection and helps strengthen the barrier for visibly clearer, calmer, more resilient skin.

No hard sell

Great skin isn't about more products. It's about the right ones.

You'll only ever leave with what actually works for your skin, never a shelf full of products headed for a drawer. And if something is not right for you, you'll hear it straight.

Why Cronulla Skin Sanctuary

Only what a therapist would put on their own skin.

Nothing here is stocked for the sake of it. Every product has earned its place in the treatment room first, chosen by the same therapists who look after Shire skin every day.

21 yrsof skin expertise behind every pick
6 therapistswho use these products
4.9from 170+ Google reviews
Meet your therapists

Client review

The most knowledgeable and talented skin clinicians that I have come across in my many, many years of having skin treatments.

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4.9 ★★★★★ 170+ Google reviews Read them all (opens in a new tab)
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Good to know

Your questions, answered.

Everything worth knowing before you buy. Still unsure which product suits you? A quick chat with a therapist sorts it out.

What are the full ingredients in the Epicutis Hydrobiome Serum?

Here's the full ingredient (INCI) list for the Hydrobiome Serum: Aqua/Water/Eau, Propanediol, Pentylene Glycol, Glycerin, Disodium Tetramethylhexadecenylcysteine Formylprolinate, Sodium Tocopheryl Phosphate, Sodium Hyaluronate, Sodium Phytate, Carbomer, Potassium Hydroxide.

How long does this product last?

Use as directed, most of the skincare here lasts around eight to twelve weeks. A little goes a long way, so resist the urge to over-apply.

Can I use this with my other products?

In most cases, yes. If you are using strong actives like retinol or exfoliating acids, introduce this gradually and space them out. Not sure? Ask our therapists.

Do you ship, or can I collect?

Both. Choose free pickup from the Cronulla clinic, or flat-rate shipping Australia-wide at checkout.

What if it doesn't suit my skin?

Get in touch, our therapists would rather help you find the right product than have you persevere with the wrong one.